Systems Biology

Iryna Lobach, PhD

Associate Professor
Epidemiology & Biostatistics

Dr. Iryna V. Lobach conducts research in applied statistics and supports the biostatistics component of biomedical research.

Her methodological research interests are motivated by challenges arising in the analyses of how an effect of the genetic basis varies by non-genetic measures (environment), what is traditionally referred to as gene-environment interaction (GxE) analyses. This type of analyses might provide valuable clues to the underlying pathophysiologic mechanisms of complex phenotypes.

Xuhui Liu, MD

Associate Professor
Orthopaedic Surgery

Dr. Liu is a well-trained and productive research scientist in the field of orthopedic surgery. He obtained his MD degree from Peking Union Medical College in China in 2001. After that, he moved to USA and received his postdoctoral research training in Orthopedic Biochemistry and Biomechanics in Baylor College of Medicine in Houston, Texas. Dr. Liu joined the Department of Orthopedic Surgery at UCSF in 2006 as a Research Biologist. He was promoted to Assistant Professor in 2008 and Associate Professor in 2015.

Guiting Lin, MD, PhD

Professor
Urology

Guiting Lin, MD, PhD received his medical degree at the Weifang Medical College in Shandong, China. Lin trained in Surgery at the Harbin Medical University in Harbin China and specialized in Urologic Surgery at Peking University, China's premier medical school located in Beijing. In 2001, Lin joined the Department of Urology as a Postdoctoral Research Fellow. He was promoted to Assistant Researcher in 2005, to Assistant Professor in 2007, to Associate Professor in 2010, and to Professor in 2010.

Ophir Klein, PhD, MD

Professor
Orofacial Sciences

Ophir Klein is Professor of Orofacial Sciences and Pediatrics, the Larry L. Hillblom Distinguished Professor in Craniofacial Anomalies, and the Charles J. Epstein Professor of Human Genetics at the University of California, San Francisco (UCSF). He serves as Chief of the Division of Medical Genetics, Chair of the Division of Craniofacial Anomalies, Interim Director of the Institute for Human Genetics, and Director of the Program in Craniofacial Biology.

Guo Huang, PhD

Associate Professor
Cardiovascular Research Institute

The regenerative potential in the animal kingdom displays striking divergence across ontogeny and phylogeny. For example, heart regeneration is remarkably robust in adult zebrafish and newborn mice while very limited in adult mammals. This presents a particular problem for patients with a heart attack who suffer from loss of millions of heart muscle cells and life-threatening functional deterioration of the heart.

Bernard Halloran, PhD

Adjunct Professor & Lecturer
Medicine

Major programs in Dr. Halloran's laboratory include stem cell aging using animal models to study the effects of aging on stem cells and bone. Projects include work with natural products from fruits for the treatment of osteoporosis, development of orthopedic stem cell-based devices to facilitate spine fusion and bone healing. Students and postdoctoral fellows are encouraged to work collaboratively with other faculty in the Departments of Medicine, Bioengineering and Orthopedics.

Douglas Gould, PhD

Professor
Opthamalogy

I earned a BSc in Biological Sciences with a specialization in Genetics from the University of Alberta in Edmonton. My interest in science derived from a desire to understand, and ideally prevent or treat, human disease and so I joined Dr. Michael Walter’s lab in the Department of Medical Genetics for my PhD work. For my thesis project I used genetic linkage analysis and candidate gene approaches in small families with highly penetrant ocular dysgenesis to identify genes that, when mutated, cause developmental glaucoma.

Lianne Gensler, MD

Associate Professor
Medicine

Dr. Lianne Gensler is a rheumatologist and serves as director of the UCSF Ankylosing Spondylitis Clinic, which is dedicated to care for this inflammatory disease.

Gensler's primary research interest is the disease progression of axial spondyloarthritis (a category that includes ankylosing spondylitis). Her research also seeks to identify predictors of osteoporosis development in patients with systemic lupus erythematosus.

Adam Ferguson, MS, PhD

Associate Professor
Neurological Surgery

Our research focuses on mechanisms of recovery after neurological trauma. Injuries to the brain and spinal cord invoke numerous, interacting biological processes that work in concert to determine recovery success. Some of these biological processes have contradictory effects at different phases of recovery.

Tejal Desai, PhD

Professor and Chair of Bioengineering and Therapeutic Sciences
Bioengineering & Therapeutic Sciences

Dr. Desai’s research brings together advanced micro and nanotechnologies, fundamental insight into cellular behavior in engineered environments, and novel pharmacologic delivery approaches to address disease treatment and clinical translation. Currently, her laboratory focuses on four highly interdisciplinary directions: 1. Hierarchical devices for enhanced cellular adhesion and paracellular drug transport; 2. Injectable and flexible nanoporous devices for rate-controlled long term release of therapeutics; 3.

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