Funding Opportunities

ARPA-H NITRO: UCSF Osteoarthritis Projects

The first ARPA-H disease targeted program:  NITRO - Novel Innovations for Tissue Regeneration in Osteoarthritis. NITRO will fund a large and ambitious effort to regenerate cartilage. Learn more here:  

Key Timelines: 

  • Proposer's Day on June 15, 2023
  • 6-page abstracts deadline June 23, 2023
  • Full Proposals deadline July 28, 2023

The NITRO program will develop technologies to enable needle-based and/or non-invasive regeneration of cartilage and bone as well as the total reconstruction of a synovial joint with load-bearing, non-immunogenic, osteo- and chondro-inductive, bioresorbable replacement joints. To accomplish this, the NITRO Program is focused on three TAs: 

• Technical Area 1 (TA1): Needle-Based and/or Non-Invasive Subchondral (SC) Bone Regeneration. Development of an IA therapeutic to fully regenerate SC bone in all synovial joint(s) in all cases of primary osteoarthritis as well as trauma- and obesity-induced secondary osteoarthritis. Proposals for TA1 must also include TA2. 

• Technical Area 2 (TA2): Needle-Based and/or Non-Invasive Cartilage Regeneration. Development of therapeutics (both IA and systemic) to fully regenerate cartilage in all synovial joints in all cases of primary osteoarthritis as well as trauma- and obesity-induced secondary osteoarthritis. Proposals for TA2 must also include TA1. 

• Technical Area 3 (TA3): Allogeneic and Autogenous Non-Immunogenic, Load-Bearing and Osteochondroinductive Total Replacement Joints. Development of autogenous and allogeneic, non-immunogenic, osteo- and chondro-inductive, load-bearing total knee replacements that requires no permanent foreign body implantation (e.g., is fully bioresorbable, no permanent fixation) and performs at or above the current standard set for artificial total knee implants. Proposals for TA3 may be submitted alone or with inclusion of both TA1 and TA2. 

Open Musculoskeletal Integrated Knowledge Exchange (Open MIKE)

Apply Online 

The Musculoskeletal (MSK) Center aims to foster collaboration among basic, clinical, and translational investigators in and beyond academia to improve musculoskeletal health. Recognizing the need for collaboration of MSK scientists with experts outside of the MSK field, we are providing support to MSKC members to host a meal for a creative and enjoyable in-person networking meeting to stimulate these interactions and to further develop new research ideas and plans to fund them. Faculty, staff, and trainees who are MSKC/CCMBM members are welcome to apply to host an event.

Open Musculoskeletal Integrated Knowledge Exchange (Open MIKE) provides funding for a CCMBM member to host a meeting (e.g., lunch or dinner) with UCSF faculty members and non-UCSF scientists who are outside of the MSK field to: 

1) brainstorm/solicit informal feedback on a study idea or research direction;

2) learn about the latest methods and techniques used in related fields;

3) identify potential collaborators;

4) promote inter-disciplinary MSK research; and

5) expand the scientists' and trainee’s professional network.

If you are not a member, you may concurrently apply for membership while your Open MIKE application is being reviewed.

Apply via the online application form today! Contact Cristal Yee for questions on this funding. 

Several mechanisms at UCSF support investigators who have musculoskeletal research questions, whether basic, computational, or clinical. One of the primary mechanisms to apply is through the UCSF Resource Allocation Program (RAP) resource.

Research funding, travel awards, and other opportunities

Grant feedback and mentorship

Grant review opportunities