Ralph Marcucio, PhD

Professor
Orthopaedic Surgery
[email protected]
+1 628 206-5366

Ralph Marcucio was born in and grew up in Amsterdam, N.Y. Ralph began his research career as an intern at The Boyce Thompson Institute while he was an undergraduate at Cornell University in Ithaca, NY. After receiving his Bachelor's Degree from Cornell University in 1990, Ralph was accepted intoCornell University's School of Agriculture PhD program. He completed his PhD in 1995. For his exemplary performance and dedication as a Graduate Teaching Assistant, Ralph was recognized by the Dean of Cornell University's School of Agriculture for his outstanding contribution to undergraduate education. After receiving his PhD, Ralph was awarded a prestigious NIH training grant to study tissue interactions that control development of the musculoskeletal system. Dr. Marcucio spent 5 years in the New York State College of Veterinary Medicine studying the origins of the musculature responsible for moving the head and jaw skeleton.

In 2000, Dr. Marcucio joined the Molecular and Cellular Biology Laboratory at the University of California, San Francisco, (UCSF). In this position, Ralph began studying how the skeleton of the face attains its shape and form. This work has resulted in the preparation of numerous manuscripts for publication in world-renowned research journals and has formed the basis for his independent research career.

In 2003, Dr. Marcucio was appointed to the faculty at UCSF as an Assistant Professor in Residence in the Department of Orthopaedic Surgery. His research program focuses on two basic science areas. First, using cutting-edge genomic technology, Dr. Marcucio is examining how the entire genome responds to orthopaedic trauma. This genome-mining approach is aimed at determining the global genome response during fracture repair and allows the possibility to generate improved, highly innovative therapies for people undergoing fracture repair. Second, Ralph is examining the role that the brain plays during normal development of the facial skeleton. Many facial birth defects have an underlying brain malformation, and the goal of the research is to generate novel therapeutic approaches that will allow correcting facial malformations prior to birth.

Dr. Marcucio is a dedicated and enthusiastic mentor to dental and medical students. His students have been invited to participate in University, State, National, and International research competitions. Dr. Marcucio reviews articles for leading journals including Cell and Tissue Research, Bone, and Mechanisms of Development, and has been an invited speaker at National and International Scientific Conferences.

Interests: Fracture healing, bone biology, stem cells, bone development, patterning, evolution

Publications

Author Correction: MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses.

Scientific data

Devine J, Vidal-García M, Liu W, Neves A, Lo Vercio LD, Green RM, Richbourg HA, Marchini M, Unger CM, Nickle AC, Radford B, Young NM, Gonzalez PN, Schuler RE, Bugacov A, Rolian C, Percival CJ, Williams T, Niswander L, Calof AL, Lander AD, Visel A, Jirik FR, Cheverud JM, Klein OD, Birnbaum RY, Merrill AE, Ackermann RR, Graf D, Hemberger M, Dean W, Forkert ND, Murray SA, Westerberg H, Marcucio RS, Hallgrímsson B

The Developmental Basis for Evolvability.

Evolvability

Benedikt Hallgrímsson, J. David Aponte, Marta Vidal-Garcia, Heather Richbourg, Rebecca Green, Nathan M. Young, James M. Cheverud, Anne L. Calof, Arthur D. Lander, Ralph S. Marcucio

MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses.

Scientific data

Devine J, Vidal-García M, Liu W, Neves A, Lo Vercio LD, Green RM, Richbourg HA, Marchini M, Unger CM, Nickle AC, Radford B, Young NM, Gonzalez PN, Schuler RE, Bugacov A, Rolian C, Percival CJ, Williams T, Niswander L, Calof AL, Lander AD, Visel A, Jirik FR, Cheverud JM, Klein OD, Birnbaum RY, Merrill AE, Ackermann RR, Graf D, Hemberger M, Dean W, Forkert ND, Murray SA, Westerberg H, Marcucio RS, Hallgrímsson B

Cellular biology of fracture healing.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Bahney CS, Zondervan RL, Allison P, Theologis A, Ashley JW, Ahn J, Miclau T, Marcucio RS, Hankenson KD

Facial surface morphology predicts variation in internal skeletal shape.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

Young NM, Sherathiya K, Gutierrez L, Nguyen E, Bekmezian S, Huang JC, Hallgrímsson B, Lee JS, Marcucio RS

Content Experts.

Larsen's Human Embryology

Richard Anderson, Parker B. Antin, Cammon Arrington, Spencer Beasley, Brian L. Black, Janice L.B. Byrne, Jon Clarke, Martyn Cobourne, Simon J. Conway, Andrew Copp, George P. Daston, Mark Davenport, Jamie Davies, Elaine Dzierzak, Darrell J.R. Evans, John F. Fallon, Richard H. Finnell, Adriana Gittenberger-deGroot, Robert G. Gourdie, Anne Grapin-Botton, Anne Greenough, Barbara F. Hales, Hiroshi Hamada, Christine Hartmann, Takayuki Inagaki, Robyn Jamieson, Chaya Kalcheim, Matthew Kelley, Thomas Knudsen, Catherine E. Krull, Ralph Marcucio, Antoon F. Moorman, Guillermo Olivier, David M. Ornitz, Maurizio Pacifici, Roger K. Patient, Alan O. Perantoni, Theodore Pysher, Maria A. Ros, Yukio Saijoh, Ramesh A. Shivdasani, Jane C. Sowden, Nancy A. Speck, Rajanarayanan Srinivasan, Michael R. Stark, David K. Stevenson, Xin Sun, Cheryll Tickle, Gijs van den Brink, Valerie Wallace, James M. Wells, Arno Wessels, Heather M. Young

Contributor contact details.

Bone Substitute Biomaterials

K.K. Mallick, S. Sprio, M. Sandri, M. Iafisco, A. Ruffini, S. Minardi, A. Tampieri, P. Bhattacharya, G.H. van Lenthe, E.B. Hunziker, T.J. Blokhuis, V. Guarino, M.G. Raucci, A. Ronca, V. Cirillo, L. Ambrosio, K.K. Mallick, J. Winnett, A. Bansiddhi, D.C. Dunand, G.C. Wang, Z.F. Lu, H. Zreiqat, C.S. Bahney, R.S. Marcucio, J. Venkatesan, S.K. Kim, L. Grøndahl, C.S. Goonasekera, K.S. Jack, S.A. Clarke, P. Walsh

The Collaborative Cross, a community resource for the genetic analysis of complex traits.

Nature genetics

Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F, Complex Trait Consortium

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