Thomas Lang, PhD

Associate Dean
Oral & Craniofacial Sciences
[email protected]
+1 415 476-1323

Thomas F. Lang, PhD, is a Professor in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco, where he has been a faculty member since 1994. Dr. Lang obtained his BA in Chemistry at the University of Chicago in 1983, and completed his PhD in Chemistry at the University of California, Berkeley in 1990, followed by a postdoctoral fellowship in Radiology Imaging at UCSF in 1992. Over the course of his 27 year career at UCSF, Dr Lang has served the University in multiple areas in addition to his role in Radiology, including as Chair of the Conflict of Interest Committee since 2010 and as Associate Dean for Research and Presidential Professor in the School of Dentistry between 2015-2020. Dr Lang has served in leadership roles outside of UCSF including as a member of the NIH Skeletal Biology and Regeneration Study Section, Musculoskeletal Alterations Team Lead at the National Space Biomedical Research Institute, Associate Editor of the Journal of Bone and Mineral Research and as an Editorial Board Member of the FASEB Journal.

The focus of Dr Lang's Research is focused on development and application of quantitative analytic methods centered on bettering our understanding of two major chronic problems that affect the growing elderly population: osteoporosis, a main cause of age-related fractures, and sarcopenia, a loss of skeletal muscle strength, endurance and function. The aim of this research is to characterize skeletal density, geometry and indices of strength from volumetric CT scans of the hip and spine, as well as similar imaging based methods to quantify skeletal muscle anatomy and function. With the growth of his research group, Dr. Lang and his group have carried out a robust program in methods development, integrating density and structured analysis with serial image registration to improve sensitivity for detecting changes in longitudinal measures, and finite element modeling in order to understand how density and structure measures of bones are related to bone strength, stiffness, and fractures.

Interests: Osteoporosis, computed tomography, bone mineral density measurements, CT and PET/CT imaging in the study of the human biology of the musculoskeletal system, bone aging

Publications: 

Skeletal effects of sleeve gastrectomy, by sex and menopausal status and compared to Roux-en-Y gastric bypass surgery.

The Journal of clinical endocrinology and metabolism

Wu KC, Wu PH, Kazakia G, Patel S, Black DM, Lang TF, Kim TY, King NJ, Hoffmann TJ, Chang H, Linfield G, Palilla S, Rogers SJ, Carter JT, Posselt AM, Schafer AL

Flickering gamma-ray flashes, the missing link between gamma glows and TGFs.

Nature

Østgaard N, Mezentsev A, Marisaldi M, Grove JE, Quick M, Christian H, Cummer S, Pazos M, Pu Y, Stanley M, Sarria D, Lang T, Schultz C, Blakeslee R, Adams I, Kroodsma R, Heymsfield G, Lehtinen N, Ullaland K, Yang S, Qureshi BH, Søndergaard J, Husa B, Walker D, Shy D, Bateman M, Bitzer P, Fullekrug M, Cohen M, Montanya J, Younes C, van der Velde O, Krehbiel P, Roncancio JA, Lopez JA, Urbani M, Santos A, Mach D

Highly dynamic gamma-ray emissions are common in tropical thunderclouds.

Nature

Marisaldi M, Østgaard N, Mezentsev A, Lang T, Grove JE, Shy D, Heymsfield GM, Krehbiel P, Thomas RJ, Stanley M, Sarria D, Schultz C, Blakeslee R, Quick MG, Christian H, Adams I, Kroodsma R, Lehtinen N, Ullaland K, Yang S, Qureshi BH, Søndergaard J, Husa B, Walker D, Bateman M, Mach D, Cummer S, Pazos M, Pu Y, Bitzer P, Fullekrug M, Cohen M, Montanya J, Younes C, van der Velde O, Roncancio JA, Lopez JA, Urbani M, Santos A

Male-Female Spatio-Temporal Differences of Age-Related Bone Changes Show Faster Bone Deterioration in Older Women at Femoral Regions Associated with Incident Hip Fracture.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Carballido-Gamio J, Marques EA, Sigurdsson S, Siggeirsdottir K, Jensen A, Sigurdsson G, Aspelund T, Gudnason V, Lang TF, Harris TB

Skeletal effects of sleeve gastrectomy, by sex and menopausal status and in comparison to Roux-en-Y gastric bypass surgery.

medRxiv : the preprint server for health sciences

Wu KC, Wu PH, Kazakia G, Patel S, Black DM, Lang TF, Kim TY, King NJ, Hoffman TJ, Chang H, Linfield G, Palilla S, Rogers SJ, Carter JT, Posselt AM, Schafer AL

A new hip fracture risk index derived from FEA-computed proximal femur fracture loads and energies-to-failure.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Cao X, Keyak JH, Sigurdsson S, Zhao C, Zhou W, Liu A, Lang TF, Deng HW, Gudnason V, Sha Q

Spine volumetric BMD and strength in premenopausal idiopathic osteoporosis: Effects of teriparatide followed by denosumab.

The Journal of clinical endocrinology and metabolism

Agarwal S, Shane E, Lang T, Shiau S, Kamanda-Kosseh M, Bucovsky M, Lappe JM, Stubby J, Recker RR, Hu Y, Wang Z, Guo XE, Cohen A

Saturated and Unsaturated Bone Marrow Lipids Have Distinct Effects on Bone Density and Fracture Risk in Older Adults.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Woods GN, Ewing SK, Schafer AL, Gudnason V, Sigurdsson S, Lang T, Hue TF, Kado DM, Vittinghoff E, Rosen C, Li X, Schwartz AV

Follicle-stimulating hormone level and changes in bone mass and body composition in older women and men.

The Journal of clinical endocrinology and metabolism

Wu KC, Ewing SK, Li X, Sigurðsson S, Guðnason V, Kado DM, Hue TF, Woods GN, Veldhuis-Vlug AG, Vittinghoff E, Zaidi M, Rosen CJ, Lang T, Kim TY, Schwartz AV, Schafer AL

Vaccines for COVID-19: An Overview.

Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)

Lane TF, Eber RM, Gansky S, Reddy MS

Accelerated decline in quadriceps area and Timed Up and Go test performance are associated with hip fracture risk in older adults with impaired kidney function.

Experimental gerontology

Marques EA, Elbejjani M, Viana JL, Gudnason V, Sigurdsson G, Lang T, Sigurdsson S, Aspelund T, Siggeirsdottir K, Launer L, Eiriksdottir G, Harris TB

Computed tomography-based skeletal muscle and adipose tissue attenuation: Variations by age, sex, and muscle.

Experimental gerontology

Figueiredo P, Marques EA, Gudnason V, Lang T, Sigurdsson S, Jonsson PV, Aspelund T, Siggeirsdottir K, Launer L, Eiriksdottir G, Harris TB

High incidence of fractures after R-CHOP-like chemotherapy for aggressive B-cell non-Hodgkin lymphomas.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Huang LW, Sun D, Link TM, Lang T, Ai W, Kaplan LD, Steinman MA, Andreadis C

Identification of non-Hodgkin lymphoma patients at risk for treatment-related vertebral density loss and fractures.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Bodden J, Sun D, Joseph GB, Huang LW, Andreadis C, Hughes-Fulford M, Lang TF, Link TM

Cigarette Smoking Is Associated With Lower Quadriceps Cross-sectional Area and Attenuation in Older Adults.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Marques EA, Elbejjani M, Frank-Wilson AW, Gudnason V, Sigurdsson G, Lang TF, Jonsson PV, Sigurdsson S, Aspelund T, Siggeirsdottir K, Launer L, Eiriksdottir G, Harris TB

Hip load capacity and yield load in men and women of all ages.

Bone

Keyak JH, Kaneko TS, Khosla S, Amin S, Atkinson EJ, Lang TF, Sibonga JD

Heterogeneous Spatial and Strength Adaptation of the Proximal Femur to Physical Activity: A Within-Subject Controlled Cross-Sectional Study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Warden SJ, Carballido-Gamio J, Weatherholt AM, Keyak JH, Yan C, Kersh ME, Lang TF, Fuchs RK

Greater Bone Marrow Adiposity Predicts Bone Loss in Older Women.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Woods GN, Ewing SK, Sigurdsson S, Kado DM, Eiriksdottir G, Gudnason V, Hue TF, Lang TF, Vittinghoff E, Harris TB, Rosen C, Xu K, Li X, Schwartz AV

Use of Quantitative Computed Tomography to Assess for Clinically-relevant Skeletal Effects of Prolonged Spaceflight on Astronaut Hips.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Sibonga JD, Spector ER, Keyak JH, Zwart SR, Smith SM, Lang TF

Resistive exercise in astronauts on prolonged spaceflights provides partial protection against spaceflight-induced bone loss.

Bone

Sibonga J, Matsumoto T, Jones J, Shapiro J, Lang T, Shackelford L, Smith SM, Young M, Keyak J, Kohri K, Ohshima H, Spector E, LeBlanc A

Hip Fracture Discrimination Based on Statistical Multi-parametric Modeling (SMPM).

Annals of biomedical engineering

Carballido-Gamio J, Yu A, Wang L, Su Y, Burghardt AJ, Lang TF, Cheng X

Hip load capacity cut-points for Astronaut Skeletal Health NASA Finite Element Strength Task Group Recommendations.

NPJ microgravity

Michalski AS, Amin S, Cheung AM, Cody DD, Keyak JH, Lang TF, Nicolella DP, Orwoll ES, Boyd SK, Sibonga JD

Changes in Lean Mass, Absolute and Relative Muscle Strength, and Physical Performance After Gastric Bypass Surgery.

The Journal of clinical endocrinology and metabolism

Alba DL, Wu L, Cawthon PM, Mulligan K, Lang T, Patel S, King NJ, Carter JT, Rogers SJ, Posselt AM, Stewart L, Shoback DM, Schafer AL

Disentangling the genetics of lean mass.

The American journal of clinical nutrition

Karasik D, Zillikens MC, Hsu YH, Aghdassi A, Akesson K, Amin N, Barroso I, Bennett DA, Bertram L, Bochud M, Borecki IB, Broer L, Buchman AS, Byberg L, Campbell H, Campos-Obando N, Cauley JA, Cawthon PM, Chambers JC, Chen Z, Cho NH, Choi HJ, Chou WC, Cummings SR, de Groot LCPGM, De Jager PL, Demuth I, Diatchenko L, Econs MJ, Eiriksdottir G, Enneman AW, Eriksson J, Eriksson JG, Estrada K, Evans DS, Feitosa MF, Fu M, Gieger C, Grallert H, Gudnason V, Lenore LJ, Hayward C, Hofman A, Homuth G, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Johnson T, Biffar R, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koller DL, Kooner JS, Kraus WE, Kritchevsky S, Kutalik Z, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Lerch MM, Lewis JR, Lill C, Lind L, Lindgren C, Liu Y, Livshits G, Ljunggren Ö, Loos RJF, Lorentzon M, Luan J, Luben RN, Malkin I, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Nethander M, Newman AB, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Peacock M, Perola M, Peters A, Prince RL, Psaty BM, Räikkönen K, Ralston SH, Ripatti S, Rivadeneira F, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schipf S, Shin CS, Smith AV, Smith SB, Soranzo N, Spector TD, Stancáková A, Stefansson K, Steinhagen-Thiessen E, Stolk L, Streeten EA, Styrkarsdottir U, Swart KMA, Thompson P, Thomson CA, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Uitterlinden AG, van Duijn CM, van Schoor NM, Vandenput L, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, J Wareham N, Waterworth D, Weedon MN, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Zhou Y, Nielson CM, Harris TB, Demissie S, Kiel DP, Ohlsson C

Chronic Kidney Disease Is Associated With Greater Bone Marrow Adiposity.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Woods GN, Ewing SK, Sigurdsson S, Kado DM, Ix JH, Hue TF, Eiriksdottir G, Xu K, Gudnason V, Lang TF, Vittinghoff E, Harris TB, Rosen CJ, Li X, Schwartz AV

Sex differences in the spatial distribution of bone in relation to incident hip fracture: Findings from the AGES-Reykjavik study.

Bone

Marques EA, Carballido-Gamio J, Gudnason V, Sigurdsson G, Sigurdsson S, Aspelund T, Siggeirsdottir K, Launer L, Eiriksdottir G, Lang T, Harris TB

Directly observed therapy of chronic hepatitis C with ledipasvir/sofosbuvir in people who inject drugs at risk of nonadherence to direct-acting antivirals.

Journal of viral hepatitis

Schütz A, Moser S, Schwanke C, Schubert R, Luhn J, Gutic E, Lang T, Schleicher M, Haltmayer H, Gschwantler M

Bone density and microarchitecture in hepatitis C and HIV-coinfected postmenopausal minority women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

T Yin M, RoyChoudhury A, Nishiyama K, Lang T, Shah J, Olender S, Ferris DC, Zeana C, Sharma A, Zingman B, Bucovsky M, Colon I, Shane E

Cigarette smoking and hip volumetric bone mineral density and cortical volume loss in older adults: The AGES-Reykjavik study.

Bone

Marques EA, Elbejjani M, Gudnason V, Sigurdsson G, Lang T, Sigurdsson S, Aspelund T, Siggeirsdottir K, Launer L, Eiriksdottir G, Harris TB

Sex hormones are negatively associated with vertebral bone marrow fat.

Bone

Mistry SD, Woods GN, Sigurdsson S, Ewing SK, Hue TF, Eiriksdottir G, Xu K, Hilton JF, Kado DM, Gudnason V, Harris TB, Rosen CJ, Lang TF, Li X, Schwartz AV

Osteocyte-Intrinsic TGF-ß Signaling Regulates Bone Quality through Perilacunar/Canalicular Remodeling.

Cell reports

Dole NS, Mazur CM, Acevedo C, Lopez JP, Monteiro DA, Fowler TW, Gludovatz B, Walsh F, Regan JN, Messina S, Evans DS, Lang TF, Zhang B, Ritchie RO, Mohammad KS, Alliston T

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Nature communications

Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stancáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Nature communications

Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stancáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP

Spatial Differences in the Distribution of Bone Between Femoral Neck and Trochanteric Fractures.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Yu A, Carballido-Gamio J, Wang L, Lang TF, Su Y, Wu X, Wang M, Wei J, Yi C, Cheng X

Associations of 24-hour sleep duration and CT-derived measurements of muscle and bone: The AGES-Reykjavik Study.

Experimental gerontology

Marques EA, Figueiredo P, Gudnason V, Lang T, Sigurdsson G, Sigurdsson S, Aspelund T, Siggeirsdottir K, Launer L, Eiriksdottir G, Harris TB

The comparability of HR-pQCT bone measurements is improved by scanning anatomically standardized regions.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Bonaretti S, Majumdar S, Lang TF, Khosla S, Burghardt AJ

Proximal Femur Volumetric Bone Mineral Density and Mortality: 13 Years of Follow-Up of the AGES-Reykjavik Study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Marques EA, Elbejjani M, Gudnason V, Sigurdsson G, Lang T, Sigurdsson S, Aspelund T, Meirelles O, Siggeirsdottir K, Launer L, Eiriksdottir G, Harris TB

11C-L-methyl methionine dynamic PET/CT of skeletal muscle: response to protein supplementation compared to L-[ring 13C6] phenylalanine infusion with serial muscle biopsy.

Annals of nuclear medicine

Arentson-Lantz EJ, Saeed IH, Frassetto LA, Masharani U, Harnish RJ, Seo Y, VanBrocklin HF, Hawkins RA, Mari-Aparici C, Pampaloni MH, Slater J, Paddon-Jones D, Lang TF

Towards human exploration of space: the THESEUS review series on muscle and bone research priorities.

NPJ microgravity

Lang T, Van Loon JJWA, Bloomfield S, Vico L, Chopard A, Rittweger J, Kyparos A, Blottner D, Vuori I, Gerzer R, Cavanagh PR

Statistical Parametric Mapping of HR-pQCT Images: A Tool for Population-Based Local Comparisons of Micro-Scale Bone Features.

Annals of biomedical engineering

Carballido-Gamio J, Bonaretti S, Kazakia GJ, Khosla S, Majumdar S, Lang TF, Burghardt AJ

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Jakobsdottir J, Wassel C, Register TC, Oei L, Alonso N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, Lang T, Bouxsein M, Latourelle J, Claussnitzer M, Siggeirsdottir K, Srikanth P, Lorentzen E, Vandenput L, Langefeld C, Raffield L, Terry G, Cox AJ, Allison MA, Criqui MH, Bowden D, Ikram MA, Mellström D, Karlsson MK, Carr J, Budoff M, Phillips C, Cupples LA, Chou WC, Myers RH, Ralston SH, Gautvik KM, Cawthon PM, Cummings S, Karasik D, Rivadeneira F, Gudnason V, Orwoll ES, Harris TB, Ohlsson C, Kiel DP, Hsu YH

Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Bonaretti S, Vilayphiou N, Chan CM, Yu A, Nishiyama K, Liu D, Boutroy S, Ghasem-Zadeh A, Boyd SK, Chapurlat R, McKay H, Shane E, Bouxsein ML, Black DM, Majumdar S, Orwoll ES, Lang TF, Khosla S, Burghardt AJ

Association of bone turnover markers with volumetric bone loss, periosteal apposition, and fracture risk in older men and women: the AGES-Reykjavik longitudinal study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Marques EA, Gudnason V, Lang T, Sigurdsson G, Sigurdsson S, Aspelund T, Siggeirsdottir K, Launer L, Eiriksdottir G, Harris TB

Effect of concomitant vitamin D deficiency or insufficiency on lumbar spine volumetric bone mineral density and trabecular bone score in primary hyperparathyroidism.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Walker MD, Saeed I, Lee JA, Zhang C, Hans D, Lang T, Silverberg SJ

Muscle Quality and Myosteatosis: Novel Associations With Mortality Risk: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study.

American Journal of Epidemiology

Reinders I, Murphy RA, Brouwer IA, Visser M, Launer L, Siggeirsdottir K, Eiriksdottir G, Gudnason V, Jonsson PV, Lang TF, Harris TB, Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study

Are bone turnover markers associated with volumetric bone density, size, and strength in older men and women? The AGES-Reykjavik study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Marques EA, Gudnason V, Sigurdsson G, Lang T, Johannesdottir F, Siggeirsdottir K, Launer L, Eiriksdottir G, Harris TB

Automatic multi-parametric quantification of the proximal femur with quantitative computed tomography.

Quantitative imaging in medicine and surgery

Carballido-Gamio J, Bonaretti S, Saeed I, Harnish R, Recker R, Burghardt AJ, Keyak JH, Harris T, Khosla S, Lang TF

Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Engelke K, Lang T, Khosla S, Qin L, Zysset P, Leslie WD, Shepherd JA, Schousboe JT

Clinical Use of Quantitative Computed Tomography-Based Advanced Techniques in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part III.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Engelke K, Lang T, Khosla S, Qin L, Zysset P, Leslie WD, Shepherd JA, Shousboe JT

Clinical Use of Quantitative Computed Tomography-Based Finite Element Analysis of the Hip and Spine in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part II.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Zysset P, Qin L, Lang T, Khosla S, Leslie WD, Shepherd JA, Schousboe JT, Engelke K

Low-Magnitude Mechanical Stimulation to Improve Bone Density in Persons of Advanced Age: A Randomized, Placebo-Controlled Trial.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Kiel DP, Hannan MT, Barton BA, Bouxsein ML, Sisson E, Lang T, Allaire B, Dewkett D, Carroll D, Magaziner J, Shane E, Leary ET, Zimmerman S, Rubin CT

Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adults: the Age, Gene/Environment Susceptibility Study.

The American journal of clinical nutrition

Harris TB, Song X, Reinders I, Lang TF, Garcia ME, Siggeirsdottir K, Sigurdsson S, Gudnason V, Eiriksdottir G, Sigurdsson G, Steingrimsdottir L, Aspelund T, Brouwer IA, Murphy RA

Fat distribution and mortality: the AGES-Reykjavik Study.

Obesity (Silver Spring, Md.)

Koster A, Murphy RA, Eiriksdottir G, Aspelund T, Sigurdsson S, Lang TF, Gudnason V, Launer LJ, Harris TB

Polyunsaturated fatty acids in relation to incident mobility disability and decline in gait speed; the Age, Gene/Environment Susceptibility-Reykjavik Study.

European journal of clinical nutrition

Reinders I, Murphy RA, Song X, Visser M, Cotch MF, Lang TF, Garcia ME, Launer LJ, Siggeirsdottir K, Eiriksdottir G, Jonsson PV, Gudnason V, Harris TB, Brouwer IA

Volumetric femoral BMD, bone geometry, and serum sclerostin levels differ between type 2 diabetic postmenopausal women with and without fragility fractures.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Heilmeier U, Carpenter DR, Patsch JM, Harnish R, Joseph GB, Burghardt AJ, Baum T, Schwartz AV, Lang TF, Link TM

Novel anthropomorphic hip phantom corrects systemic interscanner differences in proximal femoral vBMD.

Physics in medicine and biology

Bonaretti S, Carpenter RD, Saeed I, Burghardt AJ, Yu L, Bruesewitz M, Khosla S, Lang T

Circulating sclerostin associated with vertebral bone marrow fat in older men but not women.

The Journal of clinical endocrinology and metabolism

Ma YH, Schwartz AV, Sigurdsson S, Hue TF, Lang TF, Harris TB, Rosen CJ, Vittinghoff E, Eiriksdottir G, Hauksdottir AM, Siggeirsdottir K, Sigurdsson G, Oskarsdottir D, Napoli N, Palermo L, Gudnason V, Li X

Inter-scanner differences in in vivo QCT measurements of the density and strength of the proximal femur remain after correction with anthropomorphic standardization phantoms.

Medical engineering & physics

Carpenter RD, Saeed I, Bonaretti S, Schreck C, Keyak JH, Streeper T, Harris TB, Lang TF

Spatial heterogeneity in the response of the proximal femur to two lower-body resistance exercise regimens.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Lang TF, Saeed IH, Streeper T, Carballido-Gamio J, Harnish RJ, Frassetto LA, Lee SM, Sibonga JD, Keyak JH, Spiering BA, Grodsinsky CM, Bloomberg JJ, Cavanagh PR

Axial QCT: clinical applications and new developments.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Link TM, Lang TF

Structural patterns of the proximal femur in relation to age and hip fracture risk in women.

Bone

Carballido-Gamio J, Harnish R, Saeed I, Streeper T, Sigurdsson S, Amin S, Atkinson EJ, Therneau TM, Siggeirsdottir K, Cheng X, Melton LJ, Keyak JH, Gudnason V, Khosla S, Harris TB, Lang TF

Effect of finite element model loading condition on fracture risk assessment in men and women: the AGES-Reykjavik study.

Bone

Keyak JH, Sigurdsson S, Karlsdottir GS, Oskarsdottir D, Sigmarsdottir A, Kornak J, Harris TB, Sigurdsson G, Jonsson BY, Siggeirsdottir K, Eiriksdottir G, Gudnason V, Lang TF

Adipose tissue density, a novel biomarker predicting mortality risk in older adults.

The journals of gerontology. Series A, Biological sciences and medical sciences

Murphy RA, Register TC, Shively CA, Carr JJ, Ge Y, Heilbrun ME, Cummings SR, Koster A, Nevitt MC, Satterfield S, Tylvasky FA, Strotmeyer ES, Newman AB, Simonsick EM, Scherzinger A, Goodpaster BH, Launer LJ, Eiriksdottir G, Sigurdsson S, Sigurdsson G, Gudnason V, Lang TF, Kritchevsky SB, Harris TB

Vertebral bone marrow fat associated with lower trabecular BMD and prevalent vertebral fracture in older adults.

The Journal of clinical endocrinology and metabolism

Schwartz AV, Sigurdsson S, Hue TF, Lang TF, Harris TB, Rosen CJ, Vittinghoff E, Siggeirsdottir K, Sigurdsson G, Oskarsdottir D, Shet K, Palermo L, Gudnason V, Li X

Fracture risk assessment in older adults using a combination of selected quantitative computed tomography bone measures: a subanalysis of the Age, Gene/Environment Susceptibility-Reykjavik Study.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Rianon NJ, Lang TF, Siggeirsdottir K, Sigurdsson G, Eiriksdottir G, Sigurdsson S, Jonsson BY, Garcia M, Yu B, Kapadia AS, Taylor WC, Selwyn BJ, Gudnason V, Launer LJ, Harris TB

Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: a transiliac bone biopsy study.

The Journal of clinical endocrinology and metabolism

Cohen A, Dempster DW, Recker RR, Lappe JM, Zhou H, Zwahlen A, Müller R, Zhao B, Guo X, Lang T, Saeed I, Liu XS, Guo XE, Cremers S, Rosen CJ, Stein EM, Nickolas TL, McMahon DJ, Young P, Shane E

Proximal femoral density distribution and structure in relation to age and hip fracture risk in women.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Carballido-Gamio J, Harnish R, Saeed I, Streeper T, Sigurdsson S, Amin S, Atkinson EJ, Therneau TM, Siggeirsdottir K, Cheng X, Melton LJ, Keyak J, Gudnason V, Khosla S, Harris TB, Lang TF

Bisphosphonates as a supplement to exercise to protect bone during long-duration spaceflight.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Leblanc A, Matsumoto T, Jones J, Shapiro J, Lang T, Shackelford L, Smith SM, Evans H, Spector E, Ploutz-Snyder R, Sibonga J, Keyak J, Nakamura T, Kohri K, Ohshima H

Central QCT reveals lower volumetric BMD and stiffness in premenopausal women with idiopathic osteoporosis, regardless of fracture history.

The Journal of clinical endocrinology and metabolism

Cohen A, Lang TF, McMahon DJ, Liu XS, Guo XE, Zhang C, Stein EM, Dempster DW, Young P, Saeed I, Lappe JM, Recker RR, Shane E

Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Liu CT, Karasik D, Zhou Y, Hsu YH, Genant HK, Broe KE, Lang TF, Samelson EJ, Demissie S, Bouxsein ML, Cupples LA, Kiel DP

Mid-thigh cortical bone structural parameters, muscle mass and strength, and association with lower limb fractures in older men and women (AGES-Reykjavik Study).

Calcified tissue international

Johannesdottir F, Aspelund T, Siggeirsdottir K, Jonsson BY, Mogensen B, Sigurdsson S, Harris TB, Gudnason VG, Lang TF, Sigurdsson G

QCT measures of bone strength at the thoracic and lumbar spine: the Framingham Study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Samelson EJ, Christiansen BA, Demissie S, Broe KE, Louie-Gao Q, Cupples LA, Roberts BJ, Manoharam R, D'Agostino J, Lang T, Kiel DP, Bouxsein ML

Journal of Molecular Imaging and Dynamics

Quantification of changes in skeletal muscle amino acid kinetics in adult humans in response to exercise via positron-emission tomography with L-[methyl-11C]methionine

R. Harnish, T. Streeper, I. Saeed, C. Schreck, S. Dannoon, J. Slater, J. Blecha, H. VanBrocklin, M. Hernandez-Pampaloni, R. Hawkins, Y. Seo, G. Sayre and T. Lang

Lifelong physical activity in maintaining bone strength in older men and women of the Age, Gene/Environment Susceptibility-Reykjavik Study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Rianon NJ, Lang TF, Sigurdsson G, Eiriksdottir G, Sigurdsson S, Garcia M, Pajala S, Koster A, Yu B, Selwyn BJ, Taylor WC, Kapadia AS, Gudnason V, Launer LJ, Harris TB

Age-related loss of proximal femoral strength in elderly men and women: the Age Gene/Environment Susceptibility Study--Reykjavik.

Bone

Lang TF, Sigurdsson S, Karlsdottir G, Oskarsdottir D, Sigmarsdottir A, Chengshi J, Kornak J, Harris TB, Sigurdsson G, Jonsson BY, Siggeirsdottir K, Eiriksdottir G, Gudnason V, Keyak JH

Volumetric bone mineral density at the spine and hip in Chinese American and White women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Walker MD, Saeed I, McMahon DJ, Udesky J, Liu G, Lang T, Bilezikian JP

The bone-muscle relationship in men and women.

Journal of osteoporosis

Lang TF

Self-reported weight at birth predicts measures of femoral size but not volumetric BMD in eldery men: MrOS.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Javaid MK, Prieto-Alhambra D, Lui LY, Cawthon P, Arden NK, Lang T, Lane NE, Orwoll E, Barrett-Conner E, Nevitt MC, Cooper C, Cummings SR, Osteoporotic Fractures in Men (MrOS) Research Group

Male-female differences in the association between incident hip fracture and proximal femoral strength: a finite element analysis study.

Bone

Keyak JH, Sigurdsson S, Karlsdottir G, Oskarsdottir D, Sigmarsdottir A, Zhao S, Kornak J, Harris TB, Sigurdsson G, Jonsson BY, Siggeirsdottir K, Eiriksdottir G, Gudnason V, Lang TF

Acta Astronauta

Development of an integrated countermeasure device for use in long-duration spaceflight

Streeper T, Cavanagh TR, Hanson AM, Carpenter RD,Saeed I, Kornak J, Frassetto L, Grodsinsky C, Funk J, Lee SMC, Spiering BA, Bloomberg J, Mulavara A, Sibonga J, Lang T

Effects of age and sex on the strength and cortical thickness of the femoral neck.

Bone

Carpenter RD, Sigurdsson S, Zhao S, Lu Y, Eiriksdottir G, Sigurdsson G, Jonsson BY, Prevrhal S, Harris TB, Siggeirsdottir K, Guðnason V, Lang TF

Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Zmuda JM, Yerges-Armstrong LM, Moffett SP, Klei L, Kammerer CM, Roeder K, Cauley JA, Kuipers A, Ensrud KE, Nestlerode CS, Hoffman AR, Lewis CE, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Osteoporotic Fractures in Men (MrOS) Study Group

Bone density, geometry, microstructure, and stiffness: Relationships between peripheral and central skeletal sites assessed by DXA, HR-pQCT, and cQCT in premenopausal women.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Liu XS, Cohen A, Shane E, Yin PT, Stein EM, Rogers H, Kokolus SL, McMahon DJ, Lappe JM, Recker RR, Lang T, Guo XE

Fat infiltration of muscle, diabetes, and clinical fracture risk in older adults.

The Journal of clinical endocrinology and metabolism

Schafer AL, Vittinghoff E, Lang TF, Sellmeyer DE, Harris TB, Kanaya AM, Strotmeyer ES, Cawthon PM, Cummings SR, Tylavsky FA, Scherzinger AL, Schwartz AV, Health, Aging, and Body Composition (Health ABC) Study

A statistical method (cross-validation) for bone loss region detection after spaceflight.

Australasian physical & engineering sciences in medicine

Zhao Q, Li W, Li C, Chu PW, Kornak J, Lang TF, Fang J, Lu Y

Insights from the conduct of a device trial in older persons: low magnitude mechanical stimulation for musculoskeletal health.

Clinical trials (London, England)

Kiel DP, Hannan MT, Barton BA, Bouxsein ML, Lang TF, Brown KM, Shane E, Magaziner J, Zimmerman S, Rubin CT

Quantitative computed tomography.

Radiologic clinics of North America

Lang TF

Computed tomographic measurements of thigh muscle cross-sectional area and attenuation coefficient predict hip fracture: the health, aging, and body composition study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Lang T, Cauley JA, Tylavsky F, Bauer D, Cummings S, Harris TB, Health ABC Study

Candidate gene analysis of femoral neck trabecular and cortical volumetric bone mineral density in older men.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Ensrud KE, Nestlerode CS, Lewis C, Lang TF, Barrett-Connor E, Moffett SP, Hoffman AR, Ferrell RE, Orwoll ES, Zmuda JM, Osteoporotic Fractures in Men (MrOS) Study Group

Bone mineral density and prevalent osteoarthritis of the hip in older men for the Osteoporotic Fractures in Men (MrOS) Study Group.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Chaganti RK, Parimi N, Lang T, Orwoll E, Stefanick ML, Nevitt M, Lane NE, Osteoporotic Fractures in Men (MrOS) Study Group

Long-term changes in the density and structure of the human hip and spine after long-duration spaceflight. Acta Astronautica

Long-term changes in the density and structure of the human hip and spine after long-duration spaceflight. Acta Astronautica

Carpenter RD, LeBlanc AD, Evans H, Sibonga JD, Lang TF

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, MrOS Research Group

Effect of once-yearly zoledronic acid on the spine and hip as measured by quantitative computed tomography: results of the HORIZON Pivotal Fracture Trial.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Eastell R, Lang T, Boonen S, Cummings S, Delmas PD, Cauley JA, Horowitz Z, Kerzberg E, Bianchi G, Kendler D, Leung P, Man Z, Mesenbrink P, Eriksen EF, Black DM, HORIZON Pivotal Fracture Trial

Sarcopenia: etiology, clinical consequences, intervention, and assessment.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Lang T, Streeper T, Cawthon P, Baldwin K, Taaffe DR, Harris TB

Quantitative computed tomography reveals the effects of race and sex on bone size and trabecular and cortical bone density.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Saeed I, Carpenter RD, Leblanc AD, Li J, Keyak JH, Sibonga JD, Lang TF

Bone fracture risk estimation based on image similarity.

Bone

Li W, Kornak J, Harris TB, Keyak J, Li C, Lu Y, Cheng X, Lang T

Identify fracture-critical regions inside the proximal femur using statistical parametric mapping.

Bone

Li W, Kornak J, Harris T, Keyak J, Li C, Lu Y, Cheng X, Lang T

Association of coronary artery and aortic calcium with lumbar bone density: the MESA Abdominal Aortic Calcium Study.

American Journal of Epidemiology

Hyder JA, Allison MA, Wong N, Papa A, Lang TF, Sirlin C, Gapstur SM, Ouyang P, Carr JJ, Criqui MH

Alterations in muscle attenuation following detraining and retraining in resistance-trained older adults.

Gerontology

Taaffe DR, Henwood TR, Nalls MA, Walker DG, Lang TF, Harris TB

Reduction in proximal femoral strength due to long-duration spaceflight.

Bone

Keyak JH, Koyama AK, LeBlanc A, Lu Y, Lang TF

Early responsiveness of women with osteoporosis to teriparatide after therapy with alendronate or risedronate.

The Journal of clinical endocrinology and metabolism

Miller PD, Delmas PD, Lindsay R, Watts NB, Luckey M, Adachi J, Saag K, Greenspan SL, Seeman E, Boonen S, Meeves S, Lang TF, Bilezikian JP, Open-label Study to Determine How Prior Therapy with Alendronate or Risedronate in Postmenopausal Wo

Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using QCT.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Black DM, Bouxsein ML, Marshall LM, Cummings SR, Lang TF, Cauley JA, Ensrud KE, Nielson CM, Orwoll ES, Osteoporotic Fractures in Men (MrOS) Research Group

Comparison of DXA hip structural analysis with volumetric QCT.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Prevrhal S, Shepherd JA, Faulkner KG, Gaither KW, Black DM, Lang TF

Pelvic body composition measurements by quantitative computed tomography: association with recent hip fracture.

Bone

Lang T, Koyama A, Li C, Li J, Lu Y, Saeed I, Gazze E, Keyak J, Harris T, Cheng X

Race and ethnic variation in proximal femur structure and BMD among older men.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Marshall LM, Zmuda JM, Chan BK, Barrett-Connor E, Cauley JA, Ensrud KE, Lang TF, Orwoll ES, Osteoporotic Fractures in Men (MrOS) Research Group

Prediction of clinical non-spine fractures in older black and white men and women with volumetric BMD of the spine and areal BMD of the hip: the Health, Aging, and Body Composition Study*.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Mackey DC, Eby JG, Harris F, Taaffe DR, Cauley JA, Tylavsky FA, Harris TB, Lang TF, Cummings SR, Health, Aging, and Body Composition Study Group

Recovery of spaceflight-induced bone loss: bone mineral density after long-duration missions as fitted with an exponential function.

Bone

Sibonga JD, Evans HJ, Sung HG, Spector ER, Lang TF, Oganov VS, Bakulin AV, Shackelford LC, LeBlanc AD

Voxel-based modeling and quantification of the proximal femur using inter-subject registration of quantitative CT images.

Bone

Li W, Kezele I, Collins DL, Zijdenbos A, Keyak J, Kornak J, Koyama A, Saeed I, Leblanc A, Harris T, Lu Y, Lang T

What do we know about fracture risk in long-duration spaceflight?

Journal of musculoskeletal & neuronal interactions

Lang TF

Adaptation of the proximal femur to skeletal reloading after long-duration spaceflight.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Lang TF, Leblanc AD, Evans HJ, Lu Y

Dimensions and volumetric BMD of the proximal femur and their relation to age among older U.S. men.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Marshall LM, Lang TF, Lambert LC, Zmuda JM, Ensrud KE, Orwoll ES, Osteoporotic Fractures in Men (MrOS) Research Group

Prescribing practices in the management of hypertension in the Caribbean's.

Journal of human hypertension

Inamo J, Bolo M, Platon C, Atallah A, de Gaudemaris R, Chatellier G, Lang T

Increasing sex difference in bone strength in old age: The Age, Gene/Environment Susceptibility-Reykjavik study (AGES-REYKJAVIK).

Bone

Sigurdsson G, Aspelund T, Chang M, Jonsdottir B, Sigurdsson S, Eiriksdottir G, Gudmundsson A, Harris TB, Gudnason V, Lang TF

Genetic variability, haplotype structures, and ethnic diversity of hepatic transporters MDR3 (ABCB4) and bile salt export pump (ABCB11).

Drug metabolism and disposition: the biological fate of chemicals

Lang T, Haberl M, Jung D, Drescher A, Schlagenhaufer R, Keil A, Mornhinweg E, Stieger B, Kullak-Ublick GA, Kerb R

One year of alendronate after one year of parathyroid hormone (1-84) for osteoporosis.

The New England journal of medicine

Black DM, Bilezikian JP, Ensrud KE, Greenspan SL, Palermo L, Hue T, Lang TF, McGowan JA, Rosen CJ, PaTH Study Investigators

New QCT analysis approach shows the importance of fall orientation on femoral neck strength.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Carpenter RD, Beaupré GS, Lang TF, Orwoll ES, Carter DR, Osteoporotic Fractures in Men (MrOS) Study Group

Effect of spinal degenerative changes on volumetric bone mineral density of the central skeleton as measured by quantitative computed tomography.

Acta radiologica (Stockholm, Sweden : 1987)

Guglielmi G, Floriani I, Torri V, Li J, van Kuijk C, Genant HK, Lang TF

Validation of thoracic quantitative computed tomography as a method to measure bone mineral density.

Calcified tissue international

Wong M, Papa A, Lang T, Hodis HN, Labree L, Detrano R

Differences in hip quantitative computed tomography (QCT) measurements of bone mineral density and bone strength between glucocorticoid-treated and glucocorticoid-naive postmenopausal women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Lian KC, Lang TF, Keyak JH, Modin GW, Rehman Q, Do L, Lane NE

Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Lang T, LeBlanc A, Evans H, Lu Y, Genant H, Yu A

Association between bone mineral density and the use of nonsteroidal anti-inflammatory drugs and aspirin: impact of cyclooxygenase selectivity.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Carbone LD, Tylavsky FA, Cauley JA, Harris TB, Lang TF, Bauer DC, Barrow KD, Kritchevsky SB

The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis.

The New England journal of medicine

Black DM, Greenspan SL, Ensrud KE, Palermo L, McGowan JA, Lang TF, Garnero P, Bouxsein ML, Bilezikian JP, Rosen CJ, PaTH Study Investigators

Sex- and race-related differences in cross-sectional geometry and bone density of the femoral mid-shaft in older adults.

Annals of human biology

Taaffe DR, Lang TF, Fuerst T, Cauley JA, Nevitt MC, Harris TB

Poor correlation of mid-femoral measurements by CT and hip measurements by DXA in the elderly.

Aging clinical and experimental research

Taaffe DR, Lang TF, Harris TB

Comparison of the effectiveness of 2 dual-energy X-ray absorptiometers with that of total body water and computed tomography in assessing changes in body composition during weight change.

The American journal of clinical nutrition

Tylavsky FA, Lohman TG, Dockrell M, Lang T, Schoeller DA, Wan JY, Fuerst T, Cauley JA, Nevitt M, Harris TB

Daily treatment with parathyroid hormone is associated with an increase in vertebral cross-sectional area in postmenopausal women with glucocorticoid-induced osteoporosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Rehman Q, Lang TF, Arnaud CD, Modin GW, Lane NE

Quantitative computed tomography.

Seminars in musculoskeletal radiology

Guglielmi G, Lang TF

The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: a comparison with computed tomography and anthropometry.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity

Snijder MB, Visser M, Dekker JM, Seidell JC, Fuerst T, Tylavsky F, Cauley J, Lang T, Nevitt M, Harris TB

Impact of gastric banding on eating behavior and weight.

Obesity surgery

Lang T, Hauser R, Buddeberg C, Klaghofer R

Race and sex effects on the association between muscle strength, soft tissue, and bone mineral density in healthy elders: the Health, Aging, and Body Composition Study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Taaffe DR, Cauley JA, Danielson M, Nevitt MC, Lang TF, Bauer DC, Harris TB

Measurement of fat mass using DEXA: a validation study in elderly adults.

Journal of applied physiology (Bethesda, Md. : 1985)

Salamone LM, Fuerst T, Visser M, Kern M, Lang T, Dockrell M, Cauley JA, Nevitt M, Tylavsky F, Lohman TG

Advanced imaging of the macrostructure and microstructure of bone.

Hormone research

Genant HK, Gordon C, Jiang Y, Link TM, Hans D, Majumdar S, Lang TF

Advanced imaging of bone macro and micro structure.

Bone

Genant HK, Gordon C, Jiang Y, Lang TF, Link TM, Majumdar S

Assessment of vertebral bone mineral density using volumetric quantitative CT.

Journal of computer assisted tomography

Lang TF, Li J, Harris ST, Genant HK

Accuracy of cortical and trabecular bone measurements with peripheral quantitative computed tomography (pQCT).

Physics in medicine and biology

Augat P, Gordon CL, Lang TF, Iida H, Genant HK

High-resolution magnetic resonance imaging: three-dimensional trabecular bone architecture and biomechanical properties.

Bone

Majumdar S, Kothari M, Augat P, Newitt DC, Link TM, Lin JC, Lang T, Lu Y, Genant HK

Assessment of bone mineral at appendicular sites in females with fractures of the proximal femur.

Bone

Augat P, Fan B, Lane NE, Lang TF, LeHir P, Lu Y, Uffmann M, Genant HK

Anisotropy of the elastic modulus of trabecular bone specimens from different anatomical locations.

Medical engineering & physics

Augat P, Link T, Lang TF, Lin JC, Majumdar S, Genant HK

Assessment of trabecular structure using high resolution CT images and texture analysis.

Journal of computer assisted tomography

Link TM, Majumdar S, Lin JC, Augat P, Gould RG, Newitt D, Ouyang X, Lang TF, Mathur A, Genant HK

Image-based assessment of spinal trabecular bone structure from high-resolution CT images.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Gordon CL, Lang TF, Augat P, Genant HK

Vertebral fracture assessment using the lateral scoutview of computed tomography in comparison with radiographs.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Takada M, Wu CY, Lang TF, Genant HK

How can we measure bone quality?

Bailliere's clinical rheumatology

Hans D, Fuerst T, Lang T, Majumdar S, Lu Y, Genant HK, Glüer C

Spinal trabecular bone loss and fracture in American and Japanese women.

Calcified tissue international

Ito M, Lang TF, Jergas M, Ohki M, Takada M, Nakamura T, Hayashi K, Genant HK

Using the hospital emergency department as a regular source of care.

European journal of epidemiology

Lang T, Davido A, Diakité B, Agay E, Viel JF, Flicoteaux B

A preliminary evaluation of the lunar expert-XL for bone densitometry and vertebral morphometry.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Lang T, Takada M, Gee R, Wu C, Li J, Hayashi-Clark C, Schoen S, March V, Genant HK

Quantitative computed tomography at the axial and peripheral skeleton.

European radiology

Guglielmi G, Schneider P, Lang TF, Giannatempo GM, Cammisa M, Genant HK

Noninvasive assessment of bone mineral and structure: state of the art.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Genant HK, Engelke K, Fuerst T, Glüer CC, Grampp S, Harris ST, Jergas M, Lang T, Lu Y, Majumdar S, Mathur A, Takada M

Advances in the noninvasive assessment of bone density, quality, and structure.

Calcified tissue international

Genant HK, Lang TF, Engelke K, Fuerst T, Glüer C, Majumdar S, Jergas M

Quantitative computed tomography (QCT) of the lumbar spine and appendicular skeleton.

European journal of radiology

Glüer CC, Engelke K, Lang TF, Grampp S, Genant HK

Iterative concurrent reconstruction algorithms for emission computed tomography.

Physics in medicine and biology

Brown JK, Hasegawa BH, Lang TF

Noise propagation in SPECT images reconstructed using an iterative maximum-likelihood algorithm.

Physics in medicine and biology

Liew SC, Hasegawa BH, Brown JK, Lang TF

Description of a prototype emission-transmission computed tomography imaging system.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Lang TF, Hasegawa BH, Liew SC, Brown JK, Blankespoor SC, Reilly SM, Gingold EL, Cann CE

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