Rosanna Wustrack, MD

Associate Professor

Orthopaedic Surgery

+1 415 885-3800

Dr. Rosanna Wustrack is the Chief of Orthopedic Oncology and an orthopedic surgeon who specializes in the surgical diagnosis and treatment of musculoskeletal tumors and fragility fractures. Her research focuses on immunotherapy for sarcomas, functional outcomes in cancer patients, osseointegration and optimizing treatment for metastatic disease. She also is interested in global health and osteoporosis in cancer survivors.

Dr. Wustrack received an undergraduate degree from Yale University before earning a medical degree from Washington University School of Medicine in St. Louis. She completed an internship and residency in orthopedic surgery at UCSF. Subsequently, she completed fellowship training in musculoskeletal oncology at Memorial Sloan Kettering Cancer Center in New York.

Interests: Sarcoma Immunotherapy, osteoporosis, osseointegration for oncologic endoprostheses and bone anchored, percutaneous prostheses for amputees

Publications:

Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach.

Clinical cancer research : an official journal of the American Association for Cancer Research

Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MV, Vanderboon EN, Hazard FK, Cho SJ, Avedian RS, Mohler DG, Zimel M, Wustrack R, Curtis C, Sirota M, Sweet-Cordero EA

ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.

Nature communications

Pozner A, Li L, Verma SP, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, John CM, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Mortenson KL, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB

ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.

bioRxiv : the preprint server for biology

Pozner A, Verma SP, Li L, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, Mortenson KL, John C, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB

Surgical Site Infection Is Not Associated with 1-Year Progression-Free Survival After Endoprosthetic Reconstruction for Lower-Extremity Osteosarcoma: A Secondary Analysis of PARITY Study Data.

The Journal of bone and joint surgery. American volume

Jackson KJ, Sullivan CD, Zimel MN, Wustrack RL, PARITY Investigators

A Case of Hypercalcemia from PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy.

Calcified tissue international

Niu I, Hsiao EC, Wustrack R, Wysolmerski JJ, Dann P, Masharani U

Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities.

bioRxiv : the preprint server for biology

Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MAV, Vanderboon EN, Hazard FK, Cho SJ, Avedian RS, Mohler DG, Zimel M, Wustrack R, Curtis C, Sirota M, Sweet-Cordero EA

PSAT208 A Case of Hypercalcemia From PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy.

Journal of the Endocrine Society

Isabella Niu, Edward Hsiao, Rosanna Wustrack, John Wysolmerski, Pamela Dann, Umesh Masharani

Survival and failure modes of the Compress® spindle and expandable distal femur endoprosthesis among pediatric patients: A multi-institutional study.

Journal of surgical oncology

Tanaka KS, Andaya VR, Thorpe SW, Gundle KR, Hayden JB, Duong YC, Avedian RS, Mohler DG, Morse LJ, Zimel MN, O'Donnell RJ, Fang A, Randall RL, Tran TH, New C, Wustrack RL, other members of Study Group FORCE

What Are Risk Factors for and Outcomes of Late Amputation After Treatment for Lower Extremity Sarcoma: A Childhood Cancer Survivor Study Report.

Clinical orthopaedics and related research

Geiger EJ, Liu W, Srivastava DK, Bernthal NM, Weil BR, Yasui Y, Ness KK, Krull KR, Goldsby RE, Oeffinger KC, Robison LL, Dieffenbach BV, Weldon CB, Gebhardt MC, Howell R, Murphy AJ, Leisenring WM, Armstrong GT, Chow EJ, Wustrack RL

Survival of Patients With Primary Osseous Malignancies of the Mobile Spine Is Associated With Access to "Standard Treatment" Protocols.

The Journal of the American Academy of Orthopaedic Surgeons

Stroud SG, Geiger EJ, Lichtensztajn DY, Goldsby RE, Cheng I, Wustrack R, Theologis AA

Malignant triton tumor in the setting of segmental neurofibromatosis: A rare case report and review of the literature.

Interdisciplinary Neurosurgery

Andrew S. Jack, Christopher Witiw, Aaron Hockley, Charlotte J. Huie, Rosanna Wustrack, Line G. Jacques

Tumor morphology and location associate with immune cell composition in pleomorphic sarcoma.

Cancer immunology, immunotherapy : CII

Wustrack RL, Shao E, Sheridan J, Zimel M, Cho SJ, Horvai AE, Luong D, Kwek SS, Fong L, Okimoto RA

Innovations in Pediatric Prosthetics.

Journal of the Pediatric Orthopaedic Society of North America

Michelle J. Hall, Rosanna L. Wustrack, Donald R. Cummings, Richard I. Welling, Mary K. Kaleta, Kevin D. Koenig, Jennifer C. Laine, Sara J. Morgan

En bloc excision of sacroiliac chondrosarcoma aided by 3D laser printed modeling and stereotactic navigation.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Guinn JMV, Mayer RR, Li B, Dang ABC, Dang A, Wustrack R, Chou D

Complete Regression of Rhabdomyosarcoma in an Adult Secondary to Postoperative Wound Infection Following Limb Salvage Surgery: A Case Report.

The Permanente journal

Fang AS, Morse LJ, Wustrack R, Huber R, Pan M

Intraoperative Radiotherapy Without External Beam Radiotherapy in the Management of Primary Soft Tissue Sarcomas of the Extremities.

International Journal of Radiation Oncology • Biology • Physics

W.S. Chen, M. Lometti, R.L. Wustrack, M.N. Zimel, R.J. O'Donnell, A.E. Horvai, S.J. Cho, R.A. Okimoto, T.M. Jahan, A.R. Gottschalk, S.E. Braunstein

Outcomes of Elderly Patients with Soft Tissue Sarcoma of the Extremities.

International Journal of Radiation Oncology • Biology • Physics

J. Chew, S.A. Lloyd, R.A. Okimoto, A. Sabnis, E. Nakakura, C. Corvera, M.N. Zimel, A.E. Horvai, S.J. Cho, R.L. Wustrack, A.R. Gottschalk, R.J. O'Donnell, T.M. Jahan, S.E. Braunstein

Musculoskeletal Effects of Cancer and Cancer Treatment.

The Journal of the American Academy of Orthopaedic Surgeons

Wustrack R, Rao SS, Morris CD

Risk of endoprosthetic infection and impact of health-related quality of life in patients with osteosarcoma and giant cell tumor of bone; a retrospective case-control study.

Annals of Joint

Zara Butte, Kara Tanaka, Veronica Andaya, Melissa Zimel, Richard J O’Donnell, Rosanna Wustrack

Insurance impacts survival for children, adolescents, and young adults with bone and soft tissue sarcomas.

Cancer medicine

Penumarthy NL, Goldsby RE, Shiboski SC, Wustrack R, Murphy P, Winestone LE

Single cell Dissection of Resistance to anti-BCMA CAR-T cell Therapy.

Clinical Lymphoma Myeloma & Leukemia

Guy Ledergor, Elizabeth McCarthy, Nina Shah, Sandy Wong, Hewitt Chang, Frances Fan, Evans Shao, Lissa Gray, Alexander Cheung, Serena Kwek, Sophia Bylsma, Samuel Del Favero, Rosanna Wustrack, Matthew Spitzer, Jeffrey Wolf, Thomas Martin, Jimmie Ye, Lawrence Fong

Use of three-dimensional printing and intraoperative navigation in the surgical resection of metastatic acetabular osteosarcoma.

BMJ case reports

Heunis JC, Cheah JW, Sabnis AJ, Wustrack RL

Prospective study of percutaneous bone-anchored implants in transfemoral amputees: Brain-machine platform technology for external prosthetic control and feedback.

2013 6th International IEEE/EMBS Conference on Neural Engineering (NER)

Musa B. Zaid, Rosanna L. Wustrack, Matthew Garibaldi, Erik Geiger, Veronica Andaya, Richard J. O'Donnell

Current Concepts in Orthopaedic Care Disparities.

The Journal of the American Academy of Orthopaedic Surgeons

Pandya NK, Wustrack R, Metz L, Ward D

Methylene Blue-Guided Debridement as an Intraoperative Adjunct for the Surgical Treatment of Periprosthetic Joint Infection.

The Journal of arthroplasty

Shaw JD, Miller S, Plourde A, Shaw DL, Wustrack R, Hansen EN

Limb-Salvage Options in Growing Children with Malignant Bone Tumors of the Lower Extremity: A Critical Analysis Review.

JBJS reviews

Morris CD, Wustrack RL, Levin AS

Somatic and Germline TP53 Alterations in Second Malignant Neoplasms from Pediatric Cancer Survivors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Sherborne AL, Lavergne V, Yu K, Lee L, Davidson PR, Mazor T, Smirnoff IV, Horvai AE, Loh M, DuBois SG, Goldsby RE, Neglia JP, Hammond S, Robison LL, Wustrack R, Costello JF, Nakamura AO, Shannon KM, Bhatia S, Nakamura JL

Molecular Markers in Bone and Soft-Tissue Tumors.

JBJS reviews

Wustrack R, Cooper K, Weber K

A Resident-led Initiative Improves Screening and Treatment for Vitamin D Deficiency in Patients with Hip Fractures.

Clinical orthopaedics and related research

Lansdown DA, Whitaker A, Wustrack R, Sawyer A, Hansen EN

152 A Prospective Controlled Trial of the Effect of Surgeon Cost Scorecards on Operating Room Surgical Cost Reduction.

Neurosurgery

Corinna Clio Zygourakis, Victoria Valencia, Chris Moriates, Christy Boscardin, Sereina Catschegn, Andrew Goldberg, Kevin Bozic, Kent Soo Hoo, Rosanna Wustrack, Lawrence H. Pitts, Adams Dudley, Ralph Gonzales, Michael T. Lawton

How Often Does Spindle Failure Occur in Compressive Osseointegration Endoprostheses for Oncologic Reconstruction?

Clinical orthopaedics and related research

Goldman LH, Morse LJ, O'Donnell RJ, Wustrack RL

Total femoral and proximal tibial compressive osseointegration.

Current Orthopaedic Practice

Katharine N. Legaspi, Timothy V. Galan, Rosanna L. Wustrack, Richard J. O’Donnell

Intraoperative radiotherapy and limb-sparing surgery in the treatment of primary, non-metastatic extremity soft tissue sarcoma.

Journal of Radiation Oncology

Christopher L. Tinkle, Stuart Y. Tsuji, Vivian Weinberg, Rosanna Wustrack, Steve E. Braunstein, Daphne A. Haas-Kogan, Steven G. DuBois, Andrew Horvai, Thierry Jahan, Richard J. O’Donnell, Alexander R. Gottschalk

Are women with thicker cortices in the femoral shaft at higher risk of subtrochanteric/diaphyseal fractures? The study of osteoporotic fractures.

The Journal of clinical endocrinology and metabolism

Napoli N, Jin J, Peters K, Wustrack R, Burch S, Chau A, Cauley J, Ensrud K, Kelly M, Black DM

Teriparatide, vitamin D, and calcium healed bilateral subtrochanteric stress fractures in a postmenopausal woman with a 13-year history of continuous alendronate therapy.

The Journal of clinical endocrinology and metabolism

Gomberg SJ, Wustrack RL, Napoli N, Arnaud CD, Black DM

Impact of zoledronic acid on severe vertebral fractures: Results from horizon-pivotal fracture trial.

Bone

R. Wustrack, E. Seeman, C. Bucci-Rechtweg, L. Palermo, D. Black

Thumb function and appearance in thrombocytopenia: absent radius syndrome.

The Journal Of Hand Surgery

Goldfarb CA, Wustrack R, Pratt JA, Mender A, Manske PR

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Rosanna Wustrack, MD