Christine Hong, DMD, MS | UCSF Musculoskeletal Center

Associate Professor

Orofacial Sciences

+1 415 514-7413

Dr. Hong is associate professor and graduate orthodontics program director in the Division of Orthodontics. She completed her dental education cum laude from Harvard University, following which she pursued advanced training in orthodontics and an MS in oral Bbology at UCLA. Immediately following the completion of her residency, she became a faculty member at UCLA, where she was an associate professor and predoctoral orthodontic program director. Dr. Hong is a diplomate of the American Board of Orthodontics.

Dr. Hong’s clinical and research work are aimed at better understanding the biological processes underlying craniofacial bone regeneration as well as developing improved orthodontic appliances and technique in order to improve treatment outcomes for patients. She has an active research laboratory that studies the molecular mechanisms of dental stem cells in order to develop promising therapeutic targets for osteoporosis and MSC-mediated craniofacial bone regeneration.

Interests: Epigenetics, bone and cartilage biology, stem cell osteogenic differentiation

Publications

p75NTR regulates postnatal skeletal development via NGF-responsive JNK signaling.

Bone reports

Kadota-Watanabe C, Suh J, Liu Z, Yin E, Lindsey K, Lao-Ngo I, Zhao B, Wu JH, Chang IW, Kim RH, Klein OD, Hong C

p75 neurotrophin receptor regulates craniofacial growth and morphology in postnatal development.

Frontiers in cell and developmental biology

Zhao B, Suh J, Zhang Y, Yin E, Kadota-Watanabe C, Chang IW, Yaung J, Lao-Ngo I, Young NM, Kim RH, Klein OD, Hong C

Evaluation of nasal septum deviation via reformatted computed tomography (CT) imaging following expansion using RPE and MARPE.

Journal of the World federation of orthodontists

Schron D, Ran-Sukkawala M, Pereira E, Zhang Y, Hwang N, Chang IW, Lindquist K, Williams R, Peng J, Nedjat-Haiem M, Kang K, Hong C, Yoon A

Orthodontic Educational Landscape in the Contemporary Context: Insights from Educators.

Seminars in orthodontics

Allareddy V, Atsawasuwan P, Frazier-Bowers S, Hong C, Huja S, Katebi N, Lee MK, Mehta SY, Padala S, Utreja A, Vaiid N, Venugopalan SR, Wadhwa S, Yadav S

Longitudinal association of epicardial and thoracic adipose tissues with coronary and cardiac characteristics in psoriasis.

Heliyon

O'Hagan R, Hsu LY, Li H, Hong CG, Parel PM, Berg AR, Manyak GA, Bui V, Patel NH, Florida EM, Teague HL, Playford MP, Zhou W, Dey D, Chen MY, Mehta NN, Sorokin AV

A roadmap of craniofacial growth modification for children with sleep-disordered breathing: a multidisciplinary proposal.

Sleep

Yoon A, Gozal D, Kushida C, Pelayo R, Liu S, Faldu J, Hong C

In response to the Letter to the Editor regarding "A roadmap of craniofacial growth modification for children with sleep-disordered breathing: a multidisciplinary proposal".

Sleep

Yoon A, Gozal D, Pelayo R, Kushida C, Liu S, Hong C

Epigenetic Regulation of NGF-Mediated Osteogenic Differentiation in Human Dental Mesenchymal Stem Cells.

Stem cells (Dayton, Ohio)

Liu Z, Suh JS, Deng P, Bezouglaia O, Do M, Mirnia M, Cui ZK, Lee M, Aghaloo T, Wang CY, Hong C

Heritability of maxillary dental cephalometric variables among monozygotic twins, dizygotic twins and their siblings.

Clinical oral investigations

Kang GW, Kim YH, Hong C, Woo S, Sung J, Song YM, Shin JW, Chae HS

Indigenous microbiota protects development of medication-related osteonecrosis induced by periapical disease in mice.

International journal of oral science

Du W, Yang M, Kim T, Kim S, Williams DW, Esmaeili M, Hong C, Shin KH, Kang MK, Park NH, Kim RH

Impact of rapid palatal expansion on the size of adenoids and tonsils in children.

Sleep medicine

Yoon A, Abdelwahab M, Bockow R, Vakili A, Lovell K, Chang I, Ganguly R, Liu SY, Kushida C, Hong C

The ERα/KDM6B regulatory axis modulates osteogenic differentiation in human mesenchymal stem cells.

Bone research

Liu Z, Lee HL, Suh JS, Deng P, Lee CR, Bezouglaia O, Mirnia M, Chen V, Zhou M, Cui ZK, Kim RH, Lee M, Aghaloo T, Hong C, Wang CY

Psychosocial outcomes following germline multigene panel testing in an ethnically and economically diverse cohort of patients.

Cancer

Culver JO, Ricker CN, Bonner J, Kidd J, Sturgeon D, Hodan R, Kingham K, Lowstuter K, Chun NM, Lebensohn AP, Rowe-Teeter C, Levonian P, Partynski K, Lara-Otero K, Hong C, Morales Pichardo J, Mills MA, Brown K, Lerman C, Ladabaum U, McDonnell KJ, Ford JM, Gruber SB, Kurian AW, Idos GE

Growth differentiation factor 6, a repressive target of EZH2, promotes the commitment of human embryonic stem cells to mesenchymal stem cells.

Bone research

Deng P, Yu Y, Hong C, Wang CY

A study on the morphologic change of palatal alveolar bone shape after intrusion and retraction of maxillary incisors.

Scientific reports

Son EJ, Kim SJ, Hong C, Chan V, Sim HY, Ji S, Hong SY, Baik UB, Shin JW, Kim YH, Chae HS

Alveolar bone remodeling during maxillary incisor intrusion and retraction.

Progress in orthodontics

Hong SY, Shin JW, Hong C, Chan V, Baik UB, Kim YH, Chae HS

Correcting severe scissor bite in an adult.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

Baik UB, Kim Y, Sugawara J, Hong C, Park JH

Inhibition of IKK/NF-?B Signaling Enhances Differentiation of Mesenchymal Stromal Cells from Human Embryonic Stem Cells.

Stem cell reports

Deng P, Zhou C, Alvarez R, Hong C, Wang CY

Author Correction: Single CD271 marker isolates mesenchymal stem cells from human dental pulp.

International journal of oral science

Alvarez R, Lee HL, Hong C, Wang CY

Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3.

Stem cell reports

Yu Y, Deng P, Yu B, Szymanski JM, Aghaloo T, Hong C, Wang CY

PGC-1a Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ.

Cell stem cell

Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, Luo X, Hong C, Lin J, Wang CY

Removal of Pre-Existing Periodontal Inflammatory Condition before Tooth Extraction Ameliorates Medication-Related Osteonecrosis of the Jaw-Like Lesion in Mice.

The American journal of pathology

Kim T, Kim S, Song M, Lee C, Yagita H, Williams DW, Sung EC, Hong C, Shin KH, Kang MK, Park NH, Kim RH

PGC-1a Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ.

Cell stem cell

Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, Luo X, Hong C, Lin J, Wang CY

KDM4B protects against obesity and metabolic dysfunction.

Proceedings of the National Academy of Sciences of the United States of America

Cheng Y, Yuan Q, Vergnes L, Rong X, Youn JY, Li J, Yu Y, Liu W, Cai H, Lin JD, Tontonoz P, Hong C, Reue K, Wang CY

Local vs. systemic administration of bisphosphonates in rat cleft bone graft: A comparative study.

PloS one

Hong C, Quach A, Lin L, Olson J, Kwon T, Bezouglaia O, Tran J, Hoang M, Bui K, Kim RH, Tetradis S

Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3.

Stem cell reports

Yu Y, Deng P, Yu B, Szymanski JM, Aghaloo T, Hong C, Wang CY

Reducing posttreatment relapse in cleft lip palatal expansion using an injectable estrogen-nanodiamond hydrogel.

Proceedings of the National Academy of Sciences of the United States of America

Hong C, Song D, Lee DK, Lin L, Pan HC, Lee D, Deng P, Liu Z, Hadaya D, Lee HL, Mohammad A, Zhang X, Lee M, Wang CY, Ho D

Effects of monocortical and bicortical mini-implant anchorage on bone-borne palatal expansion using finite element analysis.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

Lee RJ, Moon W, Hong C

Effects of Bisphosphonate Administration on Cleft Bone Graft in a Rat Model.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

Cheng N, Park J, Olson J, Kwon T, Lee D, Lim R, Ha S, Kim R, Zhang X, Ting K, Tetradis S, Hong C

Ability of mini-implant-facilitated micro-osteoperforations to accelerate tooth movement in rats.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

Cheung T, Park J, Lee D, Kim C, Olson J, Javadi S, Lawson G, McCabe J, Moon W, Ting K, Hong C

Biomechanical effects of maxillary expansion on a patient with cleft palate: A finite element analysis.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

Lee H, Nguyen A, Hong C, Hoang P, Pham J, Ting K